Mapping breast cancer lineage in radiation and immunotherapy using the REMAP mouse
| Abigail C. Marshall, Jacqueline Vahey, M. Bagheri, Rachel Saxe, J. Fields, Fred W. Kolling, Aaron McKenna
REMAP, a lineage-tracing mouse model coupling inducible CRISPR recording with the MMTV-PyMT model of HR+ breast cancer, reveals heritable clonal programs governing metastasis and response to combined radiation and anti-PD1 immunotherapy.